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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DVL1 All Species: 23.64
Human Site: S93 Identified Species: 65
UniProt: O14640 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14640 NP_004412.2 695 75187 S93 G A H S D A G S Q G T D S H T
Chimpanzee Pan troglodytes Q5IS48 670 72833 S93 G A H S D A G S Q G T D S H T
Rhesus Macaque Macaca mulatta XP_001105770 731 78423 E109 P A H E P R A E L A P P A P P
Dog Lupus familis XP_546713 700 75601 S93 G A H S D A G S Q S T D G H T
Cat Felis silvestris
Mouse Mus musculus P51141 695 75332 S93 G A H S D A G S Q G T D S H T
Rat Rattus norvegicus Q9WVB9 695 75429 S93 G A H S D A G S Q G T D S H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422756 833 90624 S213 G S H S D A G S V C A D N Q T
Frog Xenopus laevis Q6DKE2 717 78751 S90 G S Q S D A G S V C A D I Q S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P51140 623 68898 D72 V K E E I A D D S T I L P C F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 60.5 95.2 N.A. 94.8 95.1 N.A. N.A. 55.5 65.9 N.A. N.A. 40.4 N.A. N.A. N.A.
Protein Similarity: 100 96.2 71.9 96.7 N.A. 96.6 96.9 N.A. N.A. 67.5 78 N.A. N.A. 55.5 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 100 100 N.A. N.A. 60 46.6 N.A. N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 86.6 N.A. 100 100 N.A. N.A. 73.3 60 N.A. N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 67 0 0 0 89 12 0 0 12 23 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 23 0 0 0 12 0 % C
% Asp: 0 0 0 0 78 0 12 12 0 0 0 78 0 0 0 % D
% Glu: 0 0 12 23 0 0 0 12 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 78 0 0 0 0 0 78 0 0 45 0 0 12 0 0 % G
% His: 0 0 78 0 0 0 0 0 0 0 0 0 0 56 0 % H
% Ile: 0 0 0 0 12 0 0 0 0 0 12 0 12 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % N
% Pro: 12 0 0 0 12 0 0 0 0 0 12 12 12 12 12 % P
% Gln: 0 0 12 0 0 0 0 0 56 0 0 0 0 23 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 23 0 78 0 0 0 78 12 12 0 0 45 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 56 0 0 0 67 % T
% Val: 12 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _